Published In "bone" Journal, Scientific Researches Confirm Peptan(tm) Hydrolyzed

< BACK TO COMPANY starstarstarstarstar   Business - Company Press Release
17th December 2009, 01:21am - Views: 979





Culture International ROUSSELOT SAS 1 image

Culture International ROUSSELOT SAS 2 image








MEDIA RELEASE PR37579


Published in "Bone" Journal, Scientific Researches Confirm Peptan(TM) Hydrolyzed

Collagen Benefits on Bone Health


PUTEAUX,  Dec. 16/PRNewswire-AsiaNet/ --


    

    - Studies Conducted at INRA-AgroParisTech Laboratory Under Pr.

Daniel Tomé Supervision and Published* in November 2009, in the Official 

Journal of the International Bone and Mineral Society "Bone", Reveal new 

Benefits for Peptan(TM) in Osteoporosis Prevention


    In response to customer concerns regarding long-term bone

health, Rousselot has carried out, for several years now, many studies to

demonstrate that an oral intake of Peptan(TM) may have a positive impact on

osteoporosis.


    Bone is a living dynamic metabolic system that relies on a

maintained balance between bone formation and bone resorption. Cells called

osteoblasts make bone while cells called osteoclasts resorb it. An imbalance

may lead to osteoporosis, a condition where the density and quality of bone

is reduced.


    Researchers conducted in vitro studies, and highlighted that

Peptan(TM) in bone cell culture induced a better differentiation of

osteoblasts. Those positive results have then been confirmed in vivo on

ovariectomized mice, used to simulate a postmenopausal osteoporosis, which

leads to a lower bone mineral density (BMD).


    Animals were divided into three groups: a control group (non

ovariectomized), a group of ovariectomized mice, both fed with a normal diet

and a group of ovariectomized mice that received a diet containing

Peptan(TM). After 12 weeks, the BMD of the group fed with Peptan(TM) is not

significantly different from the BMD of control group. On the contrary the

BMD of ovariectomized mice not fed with Peptan(TM) is lower.


    Confirmation of Peptan(TM) benefits on bone health has been

obtained by the measures of Carboxy Terminal Telopeptide (CTX), a usual

marker of bone resorption. CTX is significantly lower in mice fed with

PeptanTM indicating that bone resorption is reduced.


    Researchers conclude that Peptan(TM) may restore bone density in

simulated post-menopausal osteoporosis by stimulating osteoblast growth and

differentiation. This demonstrates the interest of Peptan(TM) as a bioactive

ingredient to help preventing bone loss during aging.


    *Hydrolyzed collagen improves bone metabolism and

biomechanical parameters in ovariectomized mice: an in vitro and in vivo

study. Guillerminet et al. Bone 2009.




    Part of VION N.V. (N.L.), Rousselot(R) is the worldwide leader

in gelatine and hydrolyzed collagen. VION N.V. is an internationally

operating food group that produces high-quality foods and ingredients for

humans and animals (Turnover: EUR 9.6 billion - 31,000 employees worldwide)

Culture International ROUSSELOT SAS 3 image


    SOURCE: ROUSSELOT SAS




To view this and other AsiaNet releases please visit http://www.asianetnews.net






news articles logo NEWS ARTICLES
Contact News Articles |Remove this article